Detecting fluorescence from a single DNA molecule proved difficult in practice, however. And so, in 2004, Solexa acquired the IP rights to a method called colony sequencing, developed by French scientists Pascal Mayer and Laurent Farinelli, to solve the detection problem. Colony sequencing affixed DNA fragments to a surface and amplified them over and over, generating “colonies” containing massive numbers of identical DNA strands. By reading the fluorescence from each strand in a colony simultaneously, it became possible to determine the base added at each step with much better accuracy, since random errors in individual strands would be averaged out by the consensus signal.
We’d like to thank Jukka Lehtosalo, for many discussions about the design.
，这一点在搜狗输入法下载中也有详细论述
В КСИР выступили с жестким обращением к США и Израилю22:46
So when Apple unveiled the new MacBook Neo, a lighter, more budget-friendly addition to its laptop lineup, it wasn't just the $599 price tag that caught people's attention. It was the colors.