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But that is as much as I know.
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For well-distributed points, nearest neighbor search is often near O(logn)O(\log n)O(logn) in practice. In the worst case (all points clustered tightly or along a line), it can degrade to O(n)O(n)O(n), but this is uncommon with typical spatial data.
Germline and somatic interactions define actionable genomic patterns driving acquired therapy resistance in breast cancer.